A smooth response surface algorithm for constructing a gene regulatory network

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Smooth Response Surface Algorithm for Constructing Gene Regulatory Network

A smooth response sur face algorithm is developed as an elaborate data mining technique for analyzing gene expression data and constructing gene regulatory network. A three-dimensional smooth response surface is generated to capture the biological relationship between the target and activator-repressor. This new technique is applied to functionally describe triplets of activators, repressors an...

متن کامل

A smooth response surface algorithm for constructing a gene regulatory network.

A smooth response surface (SRS) algorithm is developed as an elaborate data mining technique for analyzing gene expression data and constructing a gene regulatory network. A three-dimensional SRS is generated to capture the biological relationship between the target and activator-repressor. This new technique is applied to functionally describe triplets of activators, repressors, and targets, a...

متن کامل

A Parallel Algorithm of Constructing Gene Regulatory Networks

One of the grand challenges in post-genomic era should be construction of gene regulatory networks of organisms. As gene expression data increase exponentially, high performance computing is used to guide or even partly replace the biological experiments because traditional biological experiments to study gene regulation networks are very difficult. Gene regulatory networks obtained by parallel...

متن کامل

A Neural Network Based Generalized Response Surface Multiobjective Evolutionary Algorithm

The practical use of multiobjective optimization tools in industry is still an open issue. A strategy for reduction of objective function calls is often essential, at a fixed degree of Pareto Optimal Front (POF) approximation accuracy . To this aim an extension of single-objective NN-based GRS methods to Pareto Optimal Front (POF) approximation is proposed. Such an extension is not at all strai...

متن کامل

A gene regulatory network model for control

The activity of a biological cell is regulated by interactions between genes and proteins. In artificial intelligence, this has led to the creation of developmental gene regulatory network (GRN) models which aim to exploit these mechanisms to algorithmically build complex designs. The emerging field of GRNs for control aims to instead exploit these natural mechanisms and this ability to encode ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Physiological Genomics

سال: 2002

ISSN: 1094-8341,1531-2267

DOI: 10.1152/physiolgenomics.00060.2001